Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability

Farahnik B, Patel V, Beroukhim K, Zhu T, Abrouk M, Nakamura M, Singh R, Lee K, Bhutani T, Koo J

Psoriasis Targets and Therapy. 2016;6:105-111.

Most commonly, patients experience successful results from the use of phototherapy or biologic medications, however there are rare instances that patients do not respond well to a stand-alone treatment route. When this is the case, using the products together can produce more effective outcomes. Fortunately, combining the two therapy modalities presents very minimal risks. This allows patients to seek out an alternative treatment option when phototherapy or biologic drugs are not effective enough on their own, with narrowband UVB light therapy and biologics showing the most success in clearing psoriasis. Long-term effects of the combination have not yet been determined.