The use of combination therapy for the treatment of psoriasis

Sagransky M, Gustafson C, Feldman S

Skin and Aging. 2011.

Patients with psoriasis often experience limited results when undergoing monotherapy treatment. It is possible for successful clearance of the affected skin with just one treatment modality, but often, tolerance builds up over time and a notable decrease in efficacy is evident. In order to address this, combination therapy is often utilized. Combining phototherapy with topicals or systemics is an effective and safe therapeutic approach that minimizes adverse effects. In addition, narrowband phototherapy has also proven to be successful when combined with retinoids, methotrexate and others.